Prevalence and mechanisms of cortical superficial siderosis in cerebral amyloid angiopathy
نویسندگان
چکیده
منابع مشابه
Prevalence and mechanisms of cortical superficial siderosis in cerebral amyloid angiopathy.
OBJECTIVE We investigated the prevalence and clinical-radiologic associations of cortical superficial siderosis (cSS) in patients with probable cerebral amyloid angiopathy (CAA) compared to those with intracerebral hemorrhage (ICH) not attributed to CAA. METHODS We conducted a retrospective multicenter cohort study of 120 patients with probable CAA and 2 comparison groups: 67 patients with ei...
متن کاملSuperficial siderosis in cerebral amyloid angiopathy
With great interest, we read the recent review article by Kumar entitled “Neuroimaging in Superficial Siderosis: An In-Depth Look,” published on-line ahead of print in the American Journal of Neuroradiology in September 2009. The author provides a thorough review of neuroimaging in superficial siderosis (SS) of the central nervous system and details important underlying causes of this phenomeno...
متن کاملCerebral amyloid angiopathy, hemorrhages and superficial siderosis.
See related article, pages 2894–2897. In this issue of Stroke, Feldman and coworkers1 describe 3 subjects with clinically somewhat atypical Alzheimer Disease (AD) and with a radiologically verified superficial siderosis (SS). In 2 of these patients, a neuropathological examination confirmed AD with concomitant cerebral amyloid angiopathy (CAA) and a premortem diagnosis of SS. Thus, a linkage wa...
متن کاملCortical superficial siderosis and first-ever cerebral hemorrhage in cerebral amyloid angiopathy.
OBJECTIVE To investigate whether cortical superficial siderosis (cSS) is associated with increased risk of future first-ever symptomatic lobar intracerebral hemorrhage (ICH) in patients with cerebral amyloid angiopathy (CAA) presenting with neurologic symptoms and without ICH. METHODS Consecutive patients meeting modified Boston criteria for probable CAA in the absence of ICH from a single-ce...
متن کاملCortical superficial siderosis, APOE genotype, and hemorrhage risk in cerebral amyloid angiopathy.
The deposition of Ab amyloid in the walls of cortical and leptomeningeal blood vessels characterizes cerebral amyloid angiopathy (CAA). Clinical presentation of CAA ranges from transient neurologic events to cognitive decline to symptomatic intracerebral hemorrhage (ICH). Radiologically, CAA can present with structural brain lesions (e.g., microbleeds, white matter hyperintensities, or microinf...
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ژورنال
عنوان ژورنال: Neurology
سال: 2013
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0b013e3182a08f2c